Fig. 3

Knockdown of ADORA2A inhibits proliferation, migration, and invasion of CRC cells. (A–B) CCK8 assay of ADORA2A transfected with siRNA ADORA2A-2 and siRNA ADORA2A-3 in SW620 and HCT116. (C–D) Colony formation assay of ADORA2A transfected with siRNA ADORA2A-2 and siRNA ADORA2A-3 in SW620 and HCT116. (E–F) ADORA2A wound healing assay transfected with siRNA ADORA2A-2 and siRNA ADORA2A-3 in SW620 and HCT116. (G-H) Transwell assay of ADORA2A transfected with siRNA ADORA2A-2 and siRNA ADORA2A-3 in SW620 and HCT116. Bars:200 μm (E–F); 50 μm (G–H).