Table 2 Magnetic resonance imaging-based quantitative assessment of oculomotor muscles.

From: Magnetic resonance imaging thresholds and diagnostic accuracy in unilateral congenital superior oblique muscle palsy using the ESA method

Patients

Paralyzed eye

Non-paralyzed eye

P value

n = 60

SOM Surface (mm²)

8.40 [5.83–13.34]

13.49 [10.53–15.59]

< 0.001

SOM Area (mm²)

8.91 [6.01–15.57]

15.98 [12.63–18.85]

< 0.001

IRM Surface (mm²)

27.16 [22.32–30.85]

27.50 [22.72–31.59]

0.442

IRM Area (mm²)

32.73 [26.51–39.22]

31.95 [26.46–38.38]

0.916

Ratio PSOM/notPSOM

   

Surface

0.71 [0.48–0.94]

-

Area

0.66 [0.43–0.95]

0.573

Ratio PIR/NPIR

   

Surface

0.99 [0.90–1.12]

-

Area

0.98 [0.87–1.12]

0.518

Ratio PSOM/PIR

   

Surface

0.34 [0.22–0.46]

-

Area

0.32 [0.20–0.47]

0.520

Ratio NPSOM/NPIR

   

Surface

0.47 [0.39–0.58]

-

Area

0.48 [0.38–0.60]

0.393

Controls

   

n = 60

Right

Left

 

SOM Surface (mm²)

11.70 [8.80–15.60]

10.90 [8.80–15.75]

0.055

SOM Area (mm²)

14.16 [10.32–19.14]

14.93 [10.81–19.77]

0.803

IRM Surface (mm²)

27.70 [22.70–34.85]

28.50 [23.20–37.45]

0.066

IRM Area (mm²)

32.31 [26.85–41.28]

34.04 [28.44–41.00]

0.505

Ratio RSOM/LSOM

   

Surface

1.04 [0.95–1.14]

-

Area

1.01 [0.90–1.15]

0.257

Ratio RIR/LIR

   

Surface

0.99 [0.90–1.06]

-

Area

0.99 [0.89–1.10]

0.117

Ratio OS/IR

   

Surface

0.43 [0.37–0.51]

-

Area

0.44 [0.38–0.52]

0.472

Patients vs. controls

   

n = 120 pairs

Paralyzed eye

n = 60

Control eye

n = 60

 

SOM Surface (mm²)

8.40 [5.83–13.34]

11.70 [8.80–15.60]

< 0.001

SOM Area (mm²)

8.91 [6.01–15.57]

14.16 [10.32–19.14]

< 0.001

IRM Surface (mm²)

27.16 [22.32–30.85]

27.70 [22.70–34.85]

0.391

IRM Area (mm²)

32.73 [26.51–39.22]

32.31 [26.85–41.28]

0.555

Ratio PSOM/Control

   

Surface

0.71 [0.48–0.94]

1.04 [0.95–1.14]

< 0.001

Area

0.66 [0.43–0.95]

1.01 [0.90–1.15]

< 0.001

Ratio PIR/Control

   

Surface

0.99 [0.90–1.12]

0.99 [0.90–1.06]

0.495

Area

0.98 [0.87–1.12]

0.99 [0.89–1.10]

0.842

Data are presented as medians (interquartile range [IQR]) for continuous variables and were compared using the Mann-Whitney U test or paired Student’s t-test for comparisons within a given patient (paralyzed side vs. non-paralyzed, or right vs. left side).

IRM: inferior rectus muscle; LIR : left inferior rectus muscle; LSOM : left superior oblique muscle; NPIR: inferior rectus muscle on the non-paralyzed side; NPSOM: non-paralyzed superior oblique muscle; SOM: superior oblique muscle; PIR: inferior rectus muscle on the paralyzed side; PSOM: paralyzed superior oblique muscle; RIR: right inferior rectus muscle; RSOM: right superior oblique muscle