Table 4 Best thresholds for the diagnosis of superior oblique palsy according to SOM ratios between patients and controls, based on surface, area and composite criteria of surface OR area.

From: Magnetic resonance imaging thresholds and diagnostic accuracy in unilateral congenital superior oblique muscle palsy using the ESA method

Parameters

Cut-off point

Cut-off point

Composite threshold

Threshold

Ratio SOM surface*

0.9

Ratio SOM area

0.8

Ratio SOM surface < 0.9 or ratio SOM area < 0.8

Subject reached value of cut-off point - n (%)

51 (42.9%)

41 (34.5%)

55 (46.2%)

Subject reached value of cut-off point in paralyzed population - n (%)

47 (78.3%)

44 (73.3%)

47 (78.3%)

Area under curve (95%CI)

0.85 [0.77–0.92]

0.80 [0.72–0.89]

Sensitivity (95%CI)

0.73 [0.60–0.84]

0.63 [0.50–0.75)

0.78 [0.66–0.88]

Specificity (95%CI)

0.88 [0.77–0.95]

0.95 [0.86–0.99)

0.86 [0.75–0.94]

Positive predictive value (95%CI)

0.86 [0.74–0.94]

0.93 [0.80–0.98)

0.85 [0.73–0.94]

Negative predictive value (95%CI)

0.76 [0.65–0.86]

0.72 [0.60–0.81]

0.80 [0.68–0.89]

Positive likelihood ratio (95%CI)

6.18 [3.03–12.60]

12.46 [4.07–38.14]

5.78 [2.99–11.15]

Negative likelihood ratio (95%CI)

0.30 [0.20–0.47]

0.39 [0.28–0.54]

0.25 [0.15–0.41]

  1. SOM: superior oblique muscle; *analyses carried on 119 patients (1 datum missing in the control group).