Fig. 8 | Scientific Reports

Fig. 8

From: Explainable machine learning identifies immune-inflammatory biomarkers and therapeutic candidates in drug-resistant epilepsy

Fig. 8The alternative text for this image may have been generated using AI.

Drug–gene interactions and prioritization of therapeutic candidates. (A) Distribution of interaction types across prioritized drug–gene pairs, with inhibitors most common. (B) FDA approval status of interacting drugs (43% approved, 57% investigational). (C) Drug–gene network highlighting key pairs: P2RY12–prasugrel/ticagrelor, TNF–golimumab, IL1B–canakinumab.

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