Table 1 Descriptive and statistical analysis of epidemiological and clinicopathological characteristics of the study participants (case and control groups).
Characteristics | Cases (n = 35) | Controls (n = 35) | p-value |
|---|---|---|---|
Age (years old) | |||
Mean (SD) | 36.71 (8.89) | 36.57 (8.97) | 0.61a |
Median (min-max) | 36.00 (25–55) | 35.00 (25–56) | |
n (%) | n (%) | ||
Smoking | |||
Yes | 7 (20.00) | 3 (8.60) | 0.4b |
No | 26 (74.30) | 31 (88.60) | |
Former smoker | 2 (5.70) | 1 (2.90) | |
Alcohol consumption | |||
Yes | 25 (71.40) | 24 (68.60) | 0.053b |
No | 4 (11.40) | 10 (28.60) | |
Former consumption | 6 (17.10) | 1 (2.90) | |
Menopausal status | |||
Pre-menopause | 30 (85.70) | 30 (85.70) | > 0.9b |
Post-menopause | 5 (14.30) | 5 (14.30) | |
Use of hormonal contraceptives | |||
Never | 1 (2.90) | 8 (22.90) | 0.015b* |
Currently | 17 (48.60) | 9 (25.70) | |
Former | 17 (48.60) | 18 (51.40) | |
HPV vaccine | |||
Yes | 3 (8.60) | 6 (17.10) | 0.5b |
No | 32 (91.40) | 29 (82.90) | |
Cytology | |||
ASC-US | 4 (11.40) | − | < 0.001b* |
ASC-H | 2 (5.70) | ||
LSIL | – | ||
HSIL | 27 (77.20) | ||
Negative | 2 (5.70) | 35 (100) | |
Consolidated diagnosis | |||
CIN 2 | 4 (11.40) | − | < 0.001b* |
CIN 2/3 | 4 (11.40) | ||
CIN 3 | 27 (77.10) | ||
HPV status | |||
HPV 16 | 9 (25.70) | – | < 0.001b* |
HPV 18 | 2 (5.70) | ||
Other hr-HPV types | 16 (45.70) | ||
HPV 16 + other high-risk types | 5 (14.30) | ||
HPV 18 + other high-risk types | − | ||
Negative | 3 (8.60) | 35 (100) | |
