Fig. 4 | Scientific Reports

Fig. 4

From: Overexpression of Meis factors in late-stage retinal progenitors yields complex effects on temporal patterning and neurogenesis

Fig. 4The alternative text for this image may have been generated using AI.

MEIS overexpression’s impact on predicted target genes and progenitor cell temporal identity. (A) AUCell R package was used to generate composite scores for genes predicted to be upregulated by MEIS1 and/or MEIS2 during retinal development. Split into separate violin plots for primary and neurogenic retinal progenitor cells. (B) Scoring violin plots in RPCs for genes expressed in primary RPCs during early developmental stages. (C) Scoring violin plots for genes expressed in neurogenic RPCs during early developmental stages. P-values are indicated by * number. ns = not significant, * p < 0.05, ** p < 0.01, *** p < 0.001, and **** p < 0.0001.

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