Table 2 Absolute incidence rates per 1000 person years (95%CI) of CRC.
From: Psychiatric disorders associated with increased risk of colorectal cancer in the UK biobank cohort
No. of Cancer/No. of Accumulated Person-Years x 1000 Incidence Rare/1000 Person-Years (95%CI) | ||
|---|---|---|
Persons with Psychiatric disorders | Persons without Psychiatric disorders | |
ALL | 190/167.81 1.13 (0.98, 1.31) | 921/1750.38 0.53 (0.49, 0.56) |
By calendar year at index date | ||
2006–2010 | 28/22.59 1.24 (0.82, 1.79) | 148/237.89 0.62 (0.53, 0.73) |
2011–2015 | 116/102.27 1.13 (0.94, 1.36) | 616/1065.43 0.58 (0.53, 0.63) |
2016–2021 | 46/42.95 1.07 (0.78, 1.43) | 157/447.06 0.35 (0.30, 0.41) |
Age group | ||
<60 | 48/82.86 0.58 (0.43, 0.77) | 262/836.11 0.31 (0.28, 0.35) |
≧60 | 142/84.96 1.67 (1.41, 1.97) | 659/914.28 0.72 (0.67, 0.78) |
Gender | ||
male | 115/76.38 1.51 (1.24, 1.81) | 541/818.03 0.66 (0.61, 0.72) |
female | 75/91.44 0.82 (0.65, 1.03) | 380/932.35 0.41 (0.37, 0.45) |
Body mass index (BMI) | ||
<18.5 | 0/1.23 0 (0, 2.99) | 3/7.84 0.38 (0.08, 1.12) |
18.5–24.9 | 52/47.08 1.1 (0.83, 1.45) | 215/589.87 0.36 (0.32, 0.42) |
25.0–29.9.0.9 | 74/66.14 1.12 (0.88, 1.40) | 446/742.01 0.6 (0.55, 0.66) |
≧30.0 | 61/51.8 1.18 (0.90, 1.51) | 252/403.02 0.63 (0.55, 0.71) |
Smoking Status | ||
Ever | 149/110.48 1.35 (1.14, 1.58) | 456/709.95 0.64 (0.58, 0.70) |
Never | 40/56.63 0.71 (0.50, 0.96) | 462/1034.74 0.45 (0.41, 0.49) |
Drinking Status | ||
Ever | 181/159.85 1.13 (0.97, 1.31) | 887/1672.26 0.53 (0.50, 0.57) |
Never | 7/7.6 0.92 (0.37, 1.90) | 34/76.76 0.44 (0.31, 0.62) |
Meat Consumption | ||
Less than twice a week | 97/93.96 1.03 (0.84, 1.26) | 502/1060.89 0.47 (0.43, 0.52) |
2–4 times a week | 82/63.66 1.29 (1.02, 1.60) | 377/616.52 0.61 (0.55, 0.68) |
More than 4 times a week | 11/10.08 1.09 (0.54, 1.95) | 42/72.2 0.58 (0.42, 0.79) |
Family History | ||
Yes | 15/15.26 0.98 (0.55, 1.62) | 113/151.46 0.75 (0.61, 0.90) |
No | 175/152.55 1.15 (0.98, 1.33) | 808/1598.93 0.51 (0.47, 0.54) |
Aspirin Intake | ||
Yes | 50/28.33 1.76 (1.31, 2.33) | 167/220.32 0.76 (0.65, 0.88) |
No | 140/139.49 1.00 (0.84, 1.18) | 754/1530.07 0.49 (0.46, 0.53) |
Hormone Replacement Therapy | ||
Yes | 34/36.12 0.94 (0.65, 1.32) | 140/282.42 0.5 (0.42, 0.58) |
No | 41/54.87 0.75 (0.54, 1.01) | 239/647 0.37 (0.32, 0.42) |
Diabetes Mellitus | ||
Yes | 20/11.85 1.69 (1.03, 2.61) | 71/73.03 0.97 (0.76, 1.23) |
No | 170/155.28 1.09 (0.94, 1.27) | 848/1673.61 0.51 (0.47, 0.54) |
