Fig. 4

Probability of ATL disease-free or aggressive ATL-free survival for the three groups classified by the D + N percentage in HAS-Flow analysis Adult T-cell leukemia/lymphoma (ATL)-free and aggressive ATL-free survival analysis of the three groups classified based on HAS-Flow analysis was performed using the Kaplan–Meier method. (a) The number of years between the initial HAS-Flow analysis and the last peripheral blood smear was evaluated, and ATL development was defined as having ≥ 5% abnormal lymphocytes on examination. (b) Time from ATL development to aggressive ATL was assessed. The censored values (+) indicate the last known follow-up time of the participants who were alive without developing or aggressive ATL. A log-rank test with Bonferroni correction was performed, and the respective p-values are shown. The Cox proportional hazards model was used, and the hazard ratios and 95% confidence intervals are shown below the figure.