Table 6 Summary of significantly associated DMRs annotated to genes previously associated with autism.

From: Epigenome-wide analysis identifies DNA methylation signatures associated with the infant pupillary light reflex, a candidate intermediate phenotype for autism

DMR genomic locations (hg19)

Probes

Associated phenotype

Gene

SFARI gene-score1

chr11:19372012–19,372,234

cg23330281; cg24137774; cg25909885

Latency 14 to 24 month

NAV2

2

(strong candidate)

chr7:2968559–2,968,595

cg22989995; cg23770265

Amplitude 24 month

CARD11

2

(strong candidate)

chr13:38444227–38,444,490

cg16409955; cg23021771

Amplitude 9 to 14 month

TRPC4

3

(suggestive evidence)

  1. 1SFARI gene-scores is a ranking system that reflects the overall strength of evidence of the gene’s relevance to autism30.
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