Fig. 4 | Scientific Reports

Fig. 4

From: Ubiquitin-specific protease 14 inhibition promotes mitophagy and attenuates neural apoptosis after spinal cord injury

Fig. 4

USP14 inhibition ameliorates oxidative stress-induced mitochondrial dysfunction in vitro. (A,B) Flow cytometry was used to measure mitochondrial membrane potential by JC-1 staining to assess mitochondrial function (mean ± SD, n = 3). (C,D) Flow cytometry was used to measure mitochondrial ROS (mtROS) levels in cells from each group (mean ± SD, n = 3). Statistical analysis was performed using two-way ANOVA to calculate p-values for the mean ± standard deviation from three independent experiments. ns p > 0.05, ** p < 0.01, **** p < 0.0001.

Back to article page