Fig. 15 | Scientific Reports

Fig. 15

From: Exercise ameliorates stanozolol and cannabis co-abuse testicular damage in rats evidenced by biochemical and histological regulation of SIRT1 and STS

Fig. 15

Testis sections immunostained for caspase-3 in sedentary (A–D) and trained (E–H) rats. Sedentary groups: (A): Control group showing no caspase-3 expression, (B): Stanz group demonstrating strong brown staining of germ cells, (C): Cann group showing positive caspase-3 expression in most of seminiferous tubules. (D): Combined group showing strong brown cytoplasm and nuclear staining in all germ cells. trained groups (E): Control rats showing no caspase-3 expression in the testes. (F): Stanz group with moderately positive stained cells in the seminiferous tubules. (G): Cann group showing moderate positively stained cells in the seminiferous tubules, (H): Combined group with scattered spermatogonia, and spermatocyte cells with brown nuclear staining. The bar graph represents the score of stained tissue and expressed as mean ± SEM, significance at p < 0.05 using one-way ANOVA followed by Tukey’s multi-comparison test (n = 6).

Back to article page