Table 1 Comparison of different MIPs reported for dexamethasone DEX analysis.
Parameter | Liu et al.33 | Du et al.4 | Hang et al.34 | Adauto et al.36 | This study (MMIP10) |
|---|---|---|---|---|---|
Magnetic Core | Yes | Yes | Yes | No | Yes |
Monomer | Methacrylic acid | Methacrylic acid | DES-derived monomer | 2-Hydroxyethyl methacrylate | APBA |
Porogen | Methanol | Methanol | Deep eutectic solvent | ACN | Phosphate buffer |
Binding Solvent | ACN/water | ACN/water | ACN | Ethanol-based aqueous | Ultrapure water (pH 10) |
Binding Onset (min) | 5 | 5 | 5 | 5 | 7 |
Binding Equilibrium (min) | 30 | 180 | 120 | 180 | 120 |
Recovery (%) | 91.2–104.3 | 93.8–97.6 | 81–97 | 65.6–71.8 | 90.1 ± 7.3 |
Sample Type | Cosmetics (lotion, toner, mask) | Cosmetics | Cosmetics (lotions/creams) | Drinking & river water | River Nile water |
Magnetic separation | Yes | Yes | Yes | No | Yes |
AGREEmip Score | 0.5 | 0.67 | 0.62 | 0.61 | 0.63 |