Table 3 Survival outcomes based on TP53 expression in COAD (TCGA data via TIMER2.0).

From: Biogenic synthesis of gold nanoparticles using Coleus forskohlii leaf extract enhances anticancer activity against HT-29 cells and modulates the p53 regulated immune microenvironment in colon adenocarcinoma

Survival endpoint

Hazard ratio (HR)

95% confidence interval

p-value

Overall survival (OS)

0.61

0.48–0.78

< 0.001

Disease-specific Ssurvival (DSS)

0.59

0.45–0.77

< 0.001

Progression-free survival (PFS)

0.64

0.51–0.81

0.0002

  1. Note: HR < 1 indicates reduced risk of event in high TP53 group.
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