Table 5 Significant negative correlations between TP53 expression and chemokines in COAD.

From: Biogenic synthesis of gold nanoparticles using Coleus forskohlii leaf extract enhances anticancer activity against HT-29 cells and modulates the p53 regulated immune microenvironment in colon adenocarcinoma

Chemokine

ρ (Spearman)

p-value

Primary function

CXCL8

-0.74

< 0.001

Neutrophil recruitment,

angiogenesis

CXCL1

-0.72

< 0.001

Neutrophil chemotaxis

(ELR + CXC)

CXCL6

-0.71

< 0.001

Neutrophil activation

CXCL2

-0.7

< 0.001

Neutrophil recruitment

CCL20

-0.69

< 0.001

Treg/Th17 cell recruitment

CXCL11

-0.69

< 0.001

T cell recruitment (inflammatory)

CXCL3

-0.68

< 0.001

Neutrophil chemoattractant

CCL2

-0.67

< 0.001

Monocyte/macrophage

recruitment

CCL7

-0.66

< 0.001

Monocyte and dendritic cell

chemoattraction

CXCL5

-0.65

< 0.001

Neutrophil recruitment

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