Table 4 Correlations of DTI‑ALPS with clinical measures and FW.

From: Association of reduced DTI-ALPS index and increased free water with glymphatic system alterations in noise-induced hearing loss: a neuroimaging study

Characteristic

MTWV

HAMA

FW

r p

r p

r p

NIHL

 Mean DTI-ALPS

– 0.311 0.031*

– 0.406 0.004**†

– 0.510 <0.001***†

 Left DTI-ALPS

– 0.295 0.042*

– 0.463 <0.001***†

– 0.459 0.001**†

 Right DTI-ALPS

– 0.287 0.048*

– 0.308 0.033*

– 0.488 <0.001***†

HCs

 Mean DTI-ALPS

N/a N/a

– 0.085 0.604

– 0.124 0.444

 Left DTI-ALPS

N/a N/a

– 0.010 0.952

– 0.073 0.652

 Right DTI-ALPS

N/a N/a

– 0.176 0.277

– 0.117 0.473

  1. NIHL: noise-induced hearing loss; HCs: healthy controls; HAMA: Hamilton Anxiety Scale; MTWV: better-ear monaural threshold weighted value; DTI-ALPS: diffusion tensor imaging along perivascular space; FW: free water. Significance: *p < 0.05, **p < 0.01, ***p < 0.001(all uncorrected); †p < 0.05 (FDR-corrected).