Fig. 1 | Scientific Reports

Fig. 1

From: Salvianolic acid B inhibits the proliferation and metastasis of A549 lung cancer cells via miR-23a/PTEN/AKT pathway

Fig. 1

Sal B inhibits the metastatic ability of tumor cells in vitro. (A) Wound healing assay demonstrated that Sal B resulted in a slower closing of scratch wounds. (B) The scratch closure was recorded at 48 h. Scratch wound rate = (0 h scratch width- 48 h scratch width)/0 h scratch width×100%. (C) The results of the transwell invasion assay were measured as the number of invaded cells. (D) The quantifications of cell invasion are presented as invading cell numbers. Data were analyzed using one-way ANOVA followed by Tukey’s multiple-comparisons test with data shown as mean ± SD; n = 3. Scale bar, 50–200 μm. * Indicated the statistical significance between control group and low / high dose Sal B group. *, P < 0.05, **, P < 0.01.

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