Table 1 Blood biochemistry of WT and MMP-9 KO mice after LPS administration.

From: The hemopexin domain of matrix metalloproteinase-9 attenuates lipopolysaccharide-induced interleukin-6 secretion in liver

 

LDH (IU/L)

GPT/ALT (IU/L)

GOT/AST (IU/L)

Alb (g/dl)

WT Saline

2,118 ± 429

61.7 ± 42.7

258.0 ± 148.3

2.38 ± 0.15

WT LPS

2,647 ± 524

139.6 ± 70.6

374.8 ± 62.3

1.90 ± 0.07&&

KO Saline

2,098 ± 852

57.2 ± 33.8

279.3 ± 124.4

2.42 ± 0.19

KO LPS

3,721 ± 337&&, #

221.0 ± 148.5&

545.9 ± 225.7&

1.89 ± 0.16&&

  1. LDH: Lactic dehydrogenase, ALT: Alanine aminotransferase, AST: Aspartate aminotransferase, Alb: Albumin. WT and MMP-9 KO mice were injected with saline or 4.5 mg/kg LPS for 24 h. Data are shown as mean ± SD. n = 3–7. Statistical comparisons were conducted using Student’s t-test. & p < 0.05, && p < 0.01, compared to saline group; # p < 0.05, ## p < 0.01, compared to WT group.
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