Fig. 5 | Scientific Reports

Fig. 5

From: Plasma-activated solutions reverse chronic deltamethrin exposure induced intestinal injury via rebalancing redox homeostasis and counteracting cellular senescence

Fig. 5

The therapeutic effects of PAS primarily depend on reactive nitrogen species (A) Diagram showing PAS treatment in animals with long-term low-dose DLM exposure (n = 10). (B) Nitro-Free PAS failed to reverse DLM-induced body weight loss in mice (n = 10). (C) Nitro-Free PAS failed to reduce elevated DAI scores caused by DLM exposure (n = 10). (D, E) After Nitro-Free PAS intake, DLM-induced intestinal shortening failed to be restored (n = 10). (F,G) Compared to the 2-minute treatment, the 5-minute treatment did not increase nitrate/nitrite levels. Ion chromatography confirmed substantially diminished or abolished nitrate/nitrite levels in ddH2O treated with the nitrogen-depleted generator, validating the efficacy of nitrogen oxide-depleted PAS. Data were presented with mean ± SD. *p < 0.05, ** p < 0.01, *** p < 0.001, n.s.: no significance.

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