Table 6 Dosimetric comparison of clinical plan, AutoPlan, and rapidplan in internal (n = 20) validation cohorts. All plans were generated with jaw tracking.
From: Personalized intensity modulation radiation therapy auto-planning for esophageal cancer
Parameter | Clinical plan (CP) | Autoplan (AP) | RapidPlan (RP) | p value | |||
|---|---|---|---|---|---|---|---|
CP vs AP | AP vs RP | CP vs RP | |||||
PTV | V100% | 95 ± 0.0 | 95 ± 0.0 | 95 ± 0.0 | -- | -- | -- |
Dmax[%] | 108.1 ± 1.3 | 108.7 ± 1.2 | 109.2 ± 1.6 | 0.802 | 0.099 | 0.020 | |
Lung | V5[%] | 43.9 ± 12.0 | 41.6 ± 11.4 | 42.3 ± 11.6 | 0.069 | 0.802 | 0.254 |
V10 [%] | 30.3 ± 7.6 | 27.1 ± 7.3 | 28.4 ± 7.7 | 0.006 | 0.221 | 0.329 | |
V20[%] | 15.9 ± 5.5 | 13.5 ± 4.4 | 13.8 ± 4.5 | 0.002 | 0.659 | 0.031 | |
Dmean[Gy] | 9.0 ± 2.2 | 8.4 ± 2.2 | 8.4 ± 2.2 | <0.001 | 0.986 | <0.001 | |
Spinal Cord | Dmax[Gy] | 34.8 ± 3.3 | 38.0 ± 0.8 | 36.5 ± 1.9 | <0.001 | 0.139 | 0.139 |
Heart | V30 [%] | 32.4 ± 19.0 | 35.7 ± 18.9 | 30.2 ± 19.0 | 0.415 | 0.002 | 0.069 |
Dmean [Gy] | 21.0 ± 10.2 | 20.9 ± 9.2 | 19.6 ± 9.8 | 0.883 | 0.003 | <0.001 | |
Liver | V30[%] | 2.7 ± 3.9 | 2.8 ± 4.2 | 2.9 ± 4.2 | 0.880 | 0.970 | 0.760 |
Dmean[Gy] | 2.9 ± 3.2 | 2.8 ± 3.0 | 2.8 ± 3.1 | 0.800 | 0.710 | 0.990 | |
Kidney_L | V20 [%] | 3.2 ± 7.2 | 1.9 ± 6.3 | 2.1 ± 6.4 | 0.290 | 0.990 | 0.370 |
Dmean[Gy] | 3.2 ± 4.8 | 2.3 ± 3.6 | 2.5 ± 3.8 | 0.560 | 0.860 | 0.270 | |
Kidney_R | V20[%] | 0.0 ± 0.0 | 0.1 ± 0.2 | 0.0 ± 0.0 | 0.970 | 0.970 | 1.000 |
Dmean [Gy] | 0.9 ± 1.6 | 1.0 ± 1.6 | 1.1 ± 1.9 | 0.980 | 0.940 | 0.980 | |
CI | 0.84 ± 0.06 | 0.84 ± 0.03 | 0.83 ± 0.03 | 0.950 | 1.000 | 0.920 | |
HI | 1.06 ± 0.01 | 1.07 ± 0.01 | 1.06 ± 0.01 | 0.012 | <0.001 | 0.609 | |
MU | 839.5 ± 165.3 | 729.1 ± 181.4 | 763.8 ± 178.0 | 0.012 | 0.047 | 0.883 | |
