Fig. 1
Water consumption of 5xFAD mice with taurine supplementation. (A) Average water consumption (mL/day) using five concentrations of taurine (500, 1000, 2000, 4000 mg/kg, n = 10 per group) over the course of 5 months. (B) Average water consumption per mouse for each of the five taurine doses. (C) Average water consumption per mouse for each of the five taurine doses normalized to the animal’s weight. (D) Actual taurine dose consumed by the animal calculated from the water consumed, over the course of 5 months. (E) Effect of two different doses of taurine on water consumption in WT animals (n = 10 per group). (F) Animals were treated with either control or treated water at 2000 mg/kg/day and then switched to 4000 mg/kg/day (after the black line). There were no significant differences between the control and WT animals. (G) Total body weight at 5 months of age for WT (n = 10), untreated 5xFAD (n = 9) and 5xFAD mice treated with varying doses of taurine (n = 10 per group). There were no significant differences.
