Fig. 2

Effects of taurine treatment on cortical cytokine levels in 5xFAD mice. Luminex multiplex assay was used to analyze 10 cytokines/chemokines in the cerebral cortex of 5-month-old untreated transgenic 5xFAD mice (“5xFAD-0”, n = 9), 5xFAD mice treated with taurine from 1–5 months of age at the doses of 500 mg/kg/day (“5xFAD-500”, n = 10), 2000 mg/kg/day (“5xFAD-2000”, n = 10), or 4000 mg/kg/day (“5xFAD-4000”, n = 10), and 5-month-old non-transgenic wildtype mice (“WT”, n = 10). Dunnett’s test was used to make multiple comparisons against the untreated 5xFAD control group. Tables listing the means, standard deviation, standard error of means and effect size can be found in the supplementary document, tables S1-3.