Fig. 2 | Scientific Reports

Fig. 2

From: Novel anti-ITGA4 monoclonal antibody induces cell death via large pore formation in NK/T-cell lymphoma cells

Fig. 2

Microscopy-based analysis of mAb ANAP-induced cell death revealed the presence of giant pores. (a) A light microscopy image showing that mAb ANAP caused rapid aggregation and the death of individual NKL cells after 30 min, as evidenced by trypan blue exclusion staining. (b) Scanning electron microscopy image showing the formation of giant pores on NKL cells after 30 min incubation with mAb ANAP.

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