Table 1 Baseline characteristics of patients with acute pancreatitis before and after propensity score matching.

From: Effect of early prophylactic heparin use on prognosis in critically ill patients with acute pancreatitis: a retrospective cohort study

Variables

Original cohort

Matched cohort

No heparin (n = 320)

Early heparin (n = 532)

P-value

SMD

No heparin (n = 273)

Early heparin (n = 273)

P-value

SMD

Age (years)

59.00 (47.00, 70.25)

59.00 (45.75, 71.00)

0.878

0.009

59.00 (47.00, 71.00)

58.00 (44.00, 71.00)

0.633

0.040

Gender, Male%

187 (58.44)

304 (57.14)

0.711

0.026

162 (59.34)

150 (54.95)

0.299

0.088

Ethnicity (%)

  

0.686

0.063

  

0.887

0.038

 White

213 (66.56)

363 (68.23)

  

183 (67.03)

183 (67.03)

  

 Black

32 (10.00)

44 (8.27)

  

28 (10.26)

25 (9.16)

  

 Other

75 (23.44)

125 (23.50)

  

62 (22.71)

65 (23.81)

  

Weight (kg)

80.25 (67.65, 94.55)

81.00 (68.38, 97.60)

0.496

0.079

80.50 (69.00, 94.30)

79.50 (67.00, 93.20)

0.310

0.051

Heart rate (beats/min)

93.44 ± 18.91

96.30 ± 17.69

0.026

0.162

93.99 ± 19.02

93.81 ± 17.54

0.909

0.010

MAP (mmHg)

79.50 (72.00, 89.00)

81.00 (73.00, 92.00)

0.066

0.133

81.00 (73.00, 91.00)

80.00 (73.00, 92.00)

0.825

0.035

Respiratory rate (beats/min)

20.00 (17.00, 24.00)

21.00 (18.00, 24.00)

0.042

0.132

20.00 (17.00, 24.00)

20.00 (17.00, 23.00)

0.895

0.020

Temperature (°C)

36.90 (36.60, 37.20)

37.00 (36.70, 37.40)

0.019

0.145

36.90(36.70, 37.20)

36.90(36.70, 37.40)

0.528

0.053

WBC (K/uL)

10.55 (7.15, 15.80)

10.55 (7.20, 15.70)

0.902

0.039

10.50 (6.70, 15.70)

10.40 (7.10, 15.90)

0.915

0.025

RBC (K/uL)

3.34 (2.78, 4.01)

3.75 (3.21, 4.24)

< 0.001

0.400

3.47 (2.97, 4.19)

3.49 (3.05, 4.00)

0.882

0.018

Hemoglobin (g/L)

10.90 (9.38, 12.70)

12.00 (10.20, 13.70)

< 0.001

0.355

11.30 (9.80, 13.00)

11.20 (9.50, 12.90)

0.911

0.009

Platelets (K/uL)

163.00 (100.00, 245.25)

167.50 (117.00, 232.25)

0.199

0.033

167.00 (107.00, 250.00)

167.00 (122.00, 240.00)

0.615

0.019

Creatinine (mg/dL)

0.90 (0.60, 1.60)

0.90 (0.70, 1.70)

0.487

0.004

0.90 (0.60, 1.50)

0.90 (0.60, 1.70)

0.571

0.003

BUN (mg/dL)

18.00 (10.00, 30.25)

17.00 (11.00, 32.00)

0.762

0.054

17.00 (10.00, 30.00)

16.00 (11.00, 32.00)

0.775

0.066

ALT (IU/L)

42.00 (20.75, 131.25)

44.00 (23.00, 118.50)

0.511

0.260

40.00 (20.00, 106.00)

42.00 (23.00, 120.00)

0.384

0.049

INR

1.30 (1.10, 1.60)

1.20 (1.10, 1.40)

< 0.001

0.584

1.20 (1.10, 1.40)

1.20 (1.10, 1.40)

0.807

0.057

AG (mEq/L)

13.00 (11.00, 15.00)

13.00 (11.00, 15.00)

0.646

0.012

13.00 (11.00, 15.00)

13.00 (10.00, 15.00)

0.546

0.031

Glucose (mmol/l)

103.50 (86.00, 133.00)

113.00 (90.00, 136.25)

0.023

0.172

105.00 (89.00, 135.00)

109.00 (89.00, 133.00)

0.487

0.065

Diabetes (%)

86 (26.88)

180 (33.83)

0.034

0.147

74 (27.11)

77 (28.21)

0.774

0.024

Hypertension (%)

84 (26.25)

180 (33.83)

0.020

0.160

79 (28.94)

71 (26.01)

0.443

0.067

Obesity (%)

37 (11.56)

64 (12.03)

0.838

0.014

29 (10.62)

34 (12.45)

0.503

0.055

COPD (%)

59 (18.44)

109 (20.49)

0.466

0.051

48 (17.58)

48 (17.58)

1.000

0.000

Renal failure (%)

119 (37.19)

209 (39.29)

0.542

0.043

103 (37.73)

108 (39.56)

0.660

0.037

Heart failure (%)

44 (13.75)

75 (14.10)

0.887

0.010

43 (15.75)

38 (13.92)

0.547

0.053

Malignancy (%)

31 (9.69)

32 (6.02)

0.047

0.154

23 (8.42)

25 (9.16)

0.762

0.025

CRRT (%)

41 (12.81)

64 (12.03)

0.737

0.024

28 (10.26)

24 (8.79)

0.560

0.052

ERCP (%)

14 (4.38)

17 (3.20)

0.373

0.067

12 (4.40)

12 (4.40)

1.000

0.000

Ventilation (%)

167 (52.19)

245 (46.05)

0.083

0.123

128 (46.89)

134 (49.08)

0.607

0.044

Vasopressin (%)

47(14.69)

74 (13.91)

0.753

0.022

34 (12.45)

30 (10.99)

0.595

0.047

SOFA

6 (3, 10)

5.00 (3.00, 8.00)

0.097

0.148

5.00 (2.00, 9.00)

5.00 (3.00, 8.00)

0.892

0.039

SAPS II

36 (25, 49)

34.00 (25, 46)

0.487

0.110

35.00 (24.00, 46.00)

34.00 (26.00, 46.00)

0.950

0.010

CCI

4 (2, 6)

3.00 (2, 6)

0.186

0.104

4.00 (2.00, 5.00)

3.00 (2.00, 6.00)

0.786

0.016

  1. MAP, mean arterial pressure; WBC, white blood cell; RBC, red blood cell; BUN, blood urea nitrogen; ALT, alanine Aminotransferase; INR, international normalized ratio; AG, anion gap; COPD, chronic obstructive pulmonary disease; CRRT, continuous renal replacement therapy; ERCP, endoscopic retrograde cholangiopancreatography; SOFA, sequential organ failure assessment; SAPS II, simplified acute physiology score II; CCI, Charlson Comorbidity Index; SMD, standardized mean differences.
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