Fig. 4

Neurological function was evaluated before ICH (pre) and at days 1, 3, 5, 7, and 10 after ICH using the Forelimb placing test (A), Bederson score (B), and Longa scale (C) (n = 6/group). Data were analyzed by mixed-model repeated-measures ANOVA with Tukey’s post-hoc test. (D) Brain water content (n = 6/group) was analyzed by one-way ANOVA with Tukey’s post-hoc test. Data are presented as mean ± SD. For panels A–C, * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001 vs. Sham; # p < 0.05, ### p < 0.001 vs. ICH. For panel D, significance between groups is indicated by *** p < 0.001, **** p < 0.0001.