Table 7 Statistical comparison of the results obtained by applying the proposed method and the reported HPLC method for determination of BER in its commercial tablets.

From: Utility of fluorescamine for spectrofluorimetric quantitation of berotralstat hydrochloride in spiked human plasma and content uniformity test and evaluation of method greenness

Dosage forms

% Recoverya ± SD

Student’s t-testb

F-valueb

 

Proposed method

Reported method

  

Orladeyo® Capsules

98.49 ± 1.38

99.30 ± 1.95

0.61

1.05

  1. aThe values are the mean of three determinations.
  2. bThe tabulated values of t-test and F test at 0.05% are 2.262 and 5.050, respectively.
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