Fig. 4
From: Tissue resident memory T cells populate the human uveal tract
Previously inflamed iris tissue is enriched for genes associated with activated T cells and antigen presentation. (A) Methodological overview to compare gene expression profiles within iris tissue recovered during glaucoma surgery from donors with and without a history of uveitis. (B) Weighted gene co-expression network analysis (WGCNA) of correlations with module eigengenes (MEs) and uveitis. Pearson correlations are shown with corresponding P value in brackets. Gene ontology (GO) analysis of (C) cellular components, (D) molecular functions and (E) biological process associated with module genes. Number of genes within modules and GO terms are specified. GO terms with BH adjusted P values < 0.05 are coloured. (F) Top 20 module eigengene—gene correlations.
