Fig. 6

REACTOME pathway enrichment for cross-sectional approach (Contrasts 4–6). Pathways with FDR ≤ 0.1 are marked with a golden halo. Pathways are grouped into the pathophysiology domains: Inflammatory axis, hypoxia axis and metabolic axis (see Introduction). FDR = false discovery rate, NES = normalised enrichment score. FDR is displayed in -log10(FDR).