Fig. 1

Difference in the gut bacteriome between IIM patients and healthy controls. (A), Rarefaction curves showing the number of observed species in the two groups. (B-D), Boxplots of alpha diversity at the species level, including the number of observed bacterial species (B), Shannon index (C), and Simpson index (D). (E), Principal coordinates analysis (PCoA) based on Bray–Curtis distances at the species level, illustrating the compositional separation between the two groups. (F), Relative abundance of gut bacterial genera in healthy controls and IIM patients. (G), The top 20 differentially abundant bacterial species between the two groups. (H), PCoA based on Bray–Curtis distances of functional module compositions. I-J, Boxplots of functional diversity showing the Shannon index (I) and Simpson index (J) between the two groups at the species level. (K), The top 10 differential functional modules between IIM patients and healthy controls.