Fig. 1 | Scientific Reports

Fig. 1

From: Low-density lipoprotein cholesterol drives multinucleated giant cell formation in response to mycobacterium bovis Bacille Calmette-Guérin

Fig. 1

A Exemplary bright-field microscopy pictures of BMDM, left unstimulated or treated with the indicated dose of heat-fixed BCG for 6 days. Scale bar 100 µm. B: Quantification of N° of MGC per cm2 of culture plate after 6 days of culture stimulated with indicated dose of heat-fixed BCG. One-way ANOVA. C: Quantification of N° of MGC per cm2 of culture plate after 6 days of culture stimulated with 106 particles heat-fixed BCG/ml and increasing concentration of FBS. Reference for statistical testing: 10% FBS. Significance for exemplary meaningful comparisons is displayed. One-way ANOVA. BMDM: Bone marrow-derived macrophages; BCG: Bacille Calmette-Guérin; MGC: Multinucleated giant cell. FBS: Fetal bovine serum.

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