Fig. 1 | Scientific Reports

Fig. 1

From: Antimetastatic effects of MRTX1133 KRAS G12D specific inhibitor in a liver metastatic model of pancreatic ductal adenocarcinoma

Fig. 1

Cell proliferation of ASPC1, SW1990, and PANC1 cell lines in response to MRTX1133 treatment for two doublings. MRTX1133 concentrations of 0, 5, 25, 125, 625, 3125 nM were applied. MRTX1133 sensitivity was significantly higher in ASPC1 and SW1990 cells compared to PANC1 samples (*p ≤ 0.05). Doubling time of PANC1 was 2 days, and 4 days for SW1990 and ASPC1. Data represent the mean ± SEM of three replicates.

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