Table 2 Flow cytometric data in COVID-19 patients and control group.
From: Potential predictors of COVID-19 disease infection and severity in Egypt
The detected cells | Control group N = 45 | Cases group N = 45 | P value | R | Mild to moderate cases N = 25 | Severe to critical cases N = 20 | P value | R | |
|---|---|---|---|---|---|---|---|---|---|
CD4+ T-cells Count (cells/ mm3) | Range | 500–1200 | 255–1228 | < 0.001 | − 0.8* | 255–1228 | 284–882 | 0.09 | − 0.3 |
Mean ± SEM | 833.3 ± 33.7 | 658.8 ± 31.7 | 724.8 ± 50.3 | 577.3 ± 34.1 | |||||
PD-1% on CD3+CD4+ T cells | Range | 21–24 | 21–80 | < 0.001 | 0.56** | 21–49 | 36–80 | < 0.001 | 0.69 |
Mean ± SEM | 22.5 ± 0.16 | 39.8 ± 2.3 | 30.1 ± 1.5 | 52.1 ± 3.2 | |||||
CD8+ T-cells Count (cells/ mm3) | Range | 200–1000 | 16 -165 | < 0.001 | − 0.8* | 16–165 | 16–109 | < 0.001 | − 0.4 |
Mean ± SEM | 546.7 ± 38.9 | 68.9 ± 7 | 85.6 ± 10.5 | 48.1 ± 6 | |||||
PD-1% on CD3+CD8+ T cells | Range | 3–5 | 3–69 | < 0.001 | 0.47** | 3–11 | 3–69 | 0.002 | 0.5 |
Mean ± SEM | 3.7 ± 0.1 | 13.1 ± 1.8 | 7.8 ± 1.1 | 19.7 ± 3.4 | |||||
CD4:CD8 ratio | Range | 1–4 | 2–48 | < 0.001 | 0.43** | 7–48 | 5–22 | 0.002 | − 0.38 |
Mean ± SEM | 2.5 ± 0.2 | 13 ± 1.6 | 17 ± 2.4 | 10 ± 1.2 |
