Table 6 The difference in expression of miR-146a and miR-133a among different degrees of disease severity cases:
From: Potential predictors of COVID-19 disease infection and severity in Egypt
MiRNA | Mild to moderate cases N = 25 | Severe to critical cases N = 20 | P -value | R | ||
|---|---|---|---|---|---|---|
miRNA-146a | Total | Range | 0.2—5.3 | 0.001—0.144 | < 0.001 | − 0.57 |
Mean ± SEM | 1.2 ± 0.2 | 0.04 ± 0.01 | ||||
Upregulated cases | N (%) | 11 (44%) | 0 (0%) | < 0.001 | ||
Range | 1.2 – 5.3 | - | ||||
Mean ± SEM | 2.1 ± 0.3 | - | ||||
Downregulated cases | N (%) | 14 (56%) | 20 (100%) | |||
Range | 0.2–0.9 | 0.001—0.144 | ||||
Mean ± SEM | 0.48 ± 0.05 | 0.04 ± 0.01 | ||||
miRNA-133a | Total | Range | 1.9—374.6 | 431.2—2290.2 | < 0.001 | 0.73 |
Mean ± SEM | 99.5 ± 21.3 | 1009.4 ± 140.1 | ||||
Upregulated cases | N (%) | 25 (100%) | 20 (100%) | NA | ||
Downregulated cases | N (%) | 0 (0%) | 0 (0%) |
