Table 2 Comparison of prognostic indicators in the TBI group and the TBI + Lyc group. CRP C-reactive protein, PCT procalcitonin, GCS Glasgow coma Scale, SOFA sequential organ failure assessment, APACHE II, acute physiology and chronic health evaluation II, GOS Glasgow outcome Scale.

From: Lycopene ameliorates intestinal barrier dysfunction following traumatic brain injury by inhibiting pyroptosis

 

TBI group

(n = 35)

TBI + Lyc group

(n = 32)

P value

CRP (mg/L), median (IQR)

45.89 (20.15, 79.95)

27.85 (11.88, 50.73)

0.022

PCT (ng/mL), median (IQR)

0.27 (0.09, 0.49)

0.09 (0.05, 0.15)

0.001

Gastrointestinal complication, n (%)

22.00 (62.86%)

8.00 (25.00%)

0.002

Intestinal function assessment

   

Gastrointestinal function score

   

Grade 0, n (%)

3.00 (8.57%)

9.00 (28.12%)

0.037

Grade I, n (%)

6.00 (17.14%)

9.00 (28.12%)

0.281

Grade II, n (%)

20.00 (57.14%)

10.00 (31.25%)

0.033

Grade III, n (%)

4.00 (11.43%)

3.00 (9.38%)

1.000

Grade IV, n (%)

2.00 (5.71%)

1.00 (3.13%)

1.000

Ultrasound (scores), median (IQR)

3.00 (2.00, 4.00)

2.00 (0.00, 3.00)

0.005

Neurological deficit assessment

   

Helsinki CT (scores), median (IQR)

2.00 (2.00, 4.00)

2.00 (1.25, 2.00)

0.335

GCS (scores), median (IQR)

7.00 (4.00, 12.00)

15.00 (5.25, 15.00)

0.022

SOFA (scores), median (IQR)

5.00 (2.00, 7.00)

3.50 (1.00, 5.75)

0.083

APACHE II (scores), (mean ± SD)

17.31 ± 9.58

13.91 ± 7.80

0.117

Mortality risk (%), median (IQR)

19.88 (8.20, 37.50)

15.66 (7.86, 33.98)

0.444

Length of ICU stay (days), median (IQR)

19.00 (11.00, 30.00)

13.00 (5.00, 17.00)

0.002

Total hospital stay (days), median (IQR)

32.00 (24.00, 44.00)

23.00 (17.00, 29.75)

0.001

28-day mortality, n (%)

6.00 (17.14%)

3.00 (9.38%)

0.567

Clinical outcomes, n (%)

8.00 (22.86%)

3.00 (9.38%)

0.137

GOS (scores), median (IQR)

3.00 (2.00, 5.00)

4.00 (3.00, 5.00)

0.053