Table 1 Baseline characteristics in patients with acute pancreatitis.
Characteristic | Total (N = 459)1 | GAR | p-value2 | |
|---|---|---|---|---|
≤ 48.85 (N = 230)1 | > 48.85 (N = 229)1 | |||
Demographics | ||||
Age (year) | 56.6 (17.5) | 56.9 (19.0) | 56.3 (15.9) | 0.715 |
Gender | 0.280 | |||
Female | 211 (46.0%) | 112 (48.7%) | 99 (43.2%) | |
Male | 248 (54.0%) | 118 (51.3%) | 130 (56.8%) | |
Race | 0.286 | |||
Black | 30 (6.54%) | 13 (5.65%) | 17 (7.42%) | |
White | 285 (62.09%) | 148 (64.35%) | 137 (59.83%) | |
Other | 60 (13.07%) | 24 (10.43%) | 36 (15.72%) | |
Unknown | 84 (18.30%) | 45 (19.57%) | 39 (17.03%) | |
Height (cm) | 169.0 (10.1) | 168.0 (10.5) | 169.8 (9.7) | 0.156 |
Weight (kg) | 87.2 (23.4) | 82.6 (22.4) | 91.7 (23.6) | < 0.001 |
BMI | 31.3 (7.7) | 29.7 (7.0) | 32.7 (8.0) | 0.001 |
GCS score | 12.0 (3.7) | 12.2 (3.5) | 11.8 (3.9) | 0.185 |
SIRS score | 3.1 (0.8) | 3.0 (0.8) | 3.2 (0.7) | 0.008 |
Clinical treatments | ||||
Octreotide | 34 (7.4%) | 16 (7.0%) | 18 (7.9%) | 0.848 |
Vasopressin | 94 (20.5%) | 32 (13.9%) | 62 (27.1%) | < 0.001 |
InvasiveVent | 230 (50.1%) | 100 (43.5%) | 130 (56.8%) | 0.006 |
CRRT | 49 (10.7%) | 15 (6.5%) | 34 (14.8%) | 0.006 |
RRT | 63 (13.7%) | 22 (9.6%) | 41 (17.9%) | 0.014 |
Acute and chronic complications | ||||
AKI | 340 (74.1%) | 156 (67.8%) | 184 (80.3%) | 0.003 |
Sepsis | 293 (63.8%) | 141 (61.3%) | 152 (66.4%) | 0.301 |
Myocardial infarct | 40 (8.7%) | 21 (9.1%) | 19 (8.3%) | 0.88 |
Congestive heart failure | 66 (14.4%) | 33 (14.3%) | 33 (14.4%) | > 0.999 |
Mild liver disease | 109 (23.7%) | 56 (24.3%) | 53 (23.1%) | 0.847 |
Chronic pulmonary disease | 89 (19.4%) | 53 (23.0%) | 36 (15.7%) | 0.062 |
Cerebrovascular disease | 28 (6.1%) | 17 (7.4%) | 11 (4.8%) | 0.335 |
Hypertension | 265 (57.7%) | 131 (57.0%) | 134 (58.5%) | 0.808 |
Diabetes | 140 (30.5%) | 38 (16.5%) | 102 (44.5%) | < 0.001 |
Laboratory parameters | ||||
WBC (109 /mL) | 15.0 (8.2) | 14.0 (8.5) | 16.0 (7.8) | 0.010 |
RBC (1012/mL) | 3.9 (0.9) | 3.8 (0.8) | 4.0 (1.0) | 0.015 |
Plt (109 /mL) | 239.8 (130.6) | 227.0 (124.5) | 252.7 (135.5) | 0.035 |
Hb (g/dL) | 11.7 (2.6) | 11.6 (2.4) | 11.9 (2.8) | 0.160 |
Hct (%) (hematocrit) | 35.7 (7.6) | 35.0 (7.0) | 36.3 (8.2) | 0.055 |
PT (s) | 16.1 (8.5) | 15.9 (6.9) | 16.2 (9.9) | 0.707 |
Cr (mg/dL) | 1.4 (1.4) | 1.3 (1.5) | 1.5 (1.4) | 0.245 |
BUN (mg/dL) | 24.1 (20.1) | 21.9 (19.8) | 26.3 (20.1) | 0.018 |
Calcium (mg/dL) | 7.8 (1.2) | 8.0 (1.2) | 7.7 (1.2) | 0.008 |
Potassium (mmol/L) | 4.2 (0.9) | 4.1 (0.8) | 4.3 (1.0) | 0.050 |
Sodium (mmol/L) | 138.2 (6.3) | 138.3 (5.6) | 138.0 (7.0) | 0.633 |
ALP (U/mL) | 138.3 (133.1) | 153.1 (152.4) | 124.0 (109.6) | 0.021 |
ALT (U/mL) | 184.9 (665.1) | 229.3 (860.8) | 141.4 (383.5) | 0.167 |
AST (U/mL) | 304.9 (1,324.6) | 364.4 (1,488.8) | 247.1 (1,142.7) | 0.352 |
TB (mg/dL) | 2.0 (3.4) | 2.2 (3.7) | 1.7 (3.0) | 0.120 |
RDW | 14.9 (2.0) | 14.8 (1.9) | 14.9 (2.2) | 0.681 |
Anion gap | 15.8 (5.4) | 15.6 (5.2) | 16.0 (5.5) | 0.376 |
LD (IU/L)) | 636.0 (1,174.1) | 587.7 (1,151.0) | 688.9 (1,200.4) | 0.446 |
Clinical outcomes | ||||
LOS Hospital (day) | 20.0 (20.8) | 18.1 (20.3) | 21.9 (21.1) | 0.047 |
LOS ICU (day) | 7.6 (10.1) | 6.7 (10.1) | 8.5 (10.0) | 0.069 |
28-day mortality | 44 (9.6%) | 15 (6.5%) | 29 (12.7%) | 0.038 |