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Design and evaluation of a remote damage control surgery real-time guidance system based on HoloLens 2 in low-speed network environments
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  • Published: 06 January 2026

Design and evaluation of a remote damage control surgery real-time guidance system based on HoloLens 2 in low-speed network environments

  • Can Chen1 na1,
  • Na Kang2 na1,
  • Xin Zhong1,
  • Yijun Jia1,
  • Renqin Jiang1,
  • Chenglin Dai1,
  • Haoyang Yang1,
  • Lin Chen3,
  • Wenqiong Du1 na2 &
  • …
  • Zhaowen Zong1 na2 

Scientific Reports , Article number:  (2026) Cite this article

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We are providing an unedited version of this manuscript to give early access to its findings. Before final publication, the manuscript will undergo further editing. Please note there may be errors present which affect the content, and all legal disclaimers apply.

Subjects

  • Engineering
  • Mathematics and computing
  • Medical research

Abstract

This study aimed to develop and evaluate a remote damage control surgery (DCS) real-time guidance system based on HoloLens 2 for low-speed network environments. The system design follows a layered architecture model where the core logic is divided into network, data, service, and user layers. Data transmission in low-speed network environments is realized through multidimensional injury data encoding technology, combined with a WebSocket long-link protocol and fragmentation transmission technology. Multi-modal deep learning and decision tree algorithms are used to build an intelligent auxiliary model for injury assessment. Based on this, the HoloLens 2 immersive head-mounted display device is integrated via the Wi-Fi communication protocol to achieve multi-modal, real-time interactive surgical guidance. After the system development was completed, it was applied to four surgical teams composed of 28 students who were randomly divided into remote and control groups. An animal injury platform was used to construct a cranial trauma model for practical assessment. The remote and control groups used a guidance system and video call methods, respectively, to perform simulated remote surgery guidance. The differences in injury judgment, surgical operations, overall effectiveness scores, surgical time, and animal survival time between the two groups were compared. After the assessment, a self-made questionnaire was used for a satisfaction survey. In the remote group, the surgery operation scores were higher and the surgical time was shorter than in the control group (both P < 0.05). There were no significant differences between the two groups in injury assessment, overall effectiveness scores, or animal survival time (P > 0.05). The students scored the system’s necessity, effectiveness, compatibility, and deployment environment above 5 points. The remote DCS guidance system based on HoloLens 2 can provide remote real-time interactive guidance for DCS using mixed reality technology. The proposed method can mitigate data transmission delays in low-speed, complex network environments. In addition, the surgical guidance system can assist surgeons in improving their ability in DCS and provide real-time, efficient decision-making support, making it worthy of further application and popularization.

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Data availability

The datasets used and/or analyzed in this study are available from the corresponding author upon reasonable request.

Code availability

The code used in this study has been included in the supplementary materials.

Abbreviations

DCS:

Damage control surgery

MR:

Mixed reality

GAN:

Generative adversarial network

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Acknowledgements

We would like to thank anonymous reviewers and the editor for their comments. In addition, we want to express special thanks to Professor Huang Hongcheng and his team at Chongqing University of Posts and Telecommunications for their technical support in the field of artificial intelligence.

Author information

Author notes
  1. Can Chen and Na Kang equally to this work and should all be considered first authors.

  2. Wenqiong Du and Zhaowen Zong contributed equally to this work and should be considered Corresponding authors.

Authors and Affiliations

  1. State Key Laboratory of Trauma and Chemical Poisoning, Department for Combat Casualty Care Training, Training Base for Army Health Care, Army Medical University, Chongqing, 400038, China

    Can Chen, Xin Zhong, Yijun Jia, Renqin Jiang, Chenglin Dai, Haoyang Yang, Wenqiong Du & Zhaowen Zong

  2. Healthcare Department 9, Second Medical Center, Chinese PLA General Hospital, Beijing, 100089, China

    Na Kang

  3. International Cooperation Office, Directorate of Medical Services, Department of Logistics Support, Central Military Commission, Beijing, 100089, China

    Lin Chen

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Contributions

C. C. and K. N. performed the validation and wrote the manuscript; Z. X. and J. Y. J. contributed to the practical assessment; J. R. Q. and D. C. L. prepared the tables and tures; Y. H. Y. analyzed the data; C. L. edited the manuscript; and Z. Z. W. and D. W. Q. contributed to the study concept, data interpretation, and final revision of the manuscript.

Corresponding authors

Correspondence to Wenqiong Du or Zhaowen Zong.

Ethics declarations

Competing interests

The authors declare no competing interests.

Ethics approval and consent to participate

This study was approved by the Ethics Committee of the Army Medical University (Clinical trial number: not applicable). All methods were used in accordance with the corresponding guidelines and regulations provided by the ethics and research committees. All participants provided their informed consent to participate in the study.

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Chen, C., Kang, N., Zhong, X. et al. Design and evaluation of a remote damage control surgery real-time guidance system based on HoloLens 2 in low-speed network environments. Sci Rep (2026). https://doi.org/10.1038/s41598-025-34705-w

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  • Received: 06 July 2025

  • Accepted: 30 December 2025

  • Published: 06 January 2026

  • DOI: https://doi.org/10.1038/s41598-025-34705-w

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Keywords

  • Damage control surgery
  • Guidance system
  • HoloLens 2
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