Table 2 Endpoints characteristics of patients with and without AUD.

From: Gender differences in the association between alcohol use disorder and infertility: a nationwide population-based cohort study in Taiwan

Endpoint Characteristics

Male AUD (n = 39,930)

Male non-AUD

(n = 159,720)

Female AUD (n = 69,790)

Female non-AUD

(n = 279,160)

Follow-up duration (mean ± SD, years)

7.2 ± 3.5

7.1 ± 3.6

4.5 ± 2.7

4.6 ± 2.9

Age at infertility diagnosis (years)

34.1

36.7

32.5

34.9

Time to infertility diagnosis (mean ± SD)

3.8 ± 1.9

5.1 ± 2.4

2.3 ± 1.4

3.1 ± 1.8

Total infertility cases (n)

773

632

1,159

3,876

Infertility rate (per 1,000 PYs)

3.24

2.11

4.11

3.29

Cumulative incidence (log-rank test p-value)

< 0.001

< 0.001

< 0.001

< 0.001

  1. Data are presented as mean ± standard deviation (SD) for continuous variables, unless otherwise specified. Follow-up duration refers to the time from index date to the earliest of infertility diagnosis, withdrawal, death, or study endpoint. Time to infertility diagnosis indicates the mean duration from index date to the occurrence of infertility among those diagnosed. Infertility rate is expressed per 1,000 person-years (PYs) of follow-up. Cumulative incidence p-values are derived from the log-rank test. AUD = Alcohol Use Disorder.
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