Table 1 Parameters used for synthetic degradation of CLSM training data.
From: Enhanced confocal microscopy with physics-guided autoencoders via synthetic noise modeling
Degradation component | Parameter specification |
|---|---|
Point spread function (PSF) | Airy disk model, NA = 1.4, λ = 500 nm |
Photon shot noise | Poisson distribution, scale = 0.1 |
Dark current noise | Additive Gaussian noise, σ = 0.05 |
Speckle noise | Multiplicative Gaussian noise, σ = 0.05 |
Motion blur | Linear kernel, 5 pixels, random orientation |
Laser power fluctuations | Multiplicative Gaussian scaling, σ = 0.05 |
Undersampling | 20% random pixel deletion (binary mask) |
Attenuation (post-PSF) | Exponential decay co-efficient = 1.20 |
