Table 3 Relationships between sarcomere-associated mutation and fiber functions.

From: Effects of genetic mutations on left ventricular myocardial mechanics and fibrosis patterns in hypertrophic cardiomyopathy

 

Average LV-CSmyo

Univariate

Multivariable

β

p

β

p

SM

0.276

0.001

0.239

0.008

% LGE mass

0.297

0.001

0.267

0.004

Midepicardial LGE

0.177

0.042

− 0.028

0.773

Average ECV

0.287

0.001

*0.205

*0.032

LV mass index by CMR

0.052

0.555

  

Apical HCM

− 0.104

0.236

  
 

LV-GLSmyo

Univariate

Multivariable

β

p

β

p

SM

0.095

0.275

  

% LGE mass

0.250

0.004

0.211

0.015

Midepicardial LGE

0.148

0.088

  

Average ECV

0.214

0.017

*0.186

*0.035

LV mass index by CMR

0.229

0.008

0.183

0.034

Apical HCM

-0.020

0.822

  
  1. See abbreviations in Tables 1 and 2. *average ECV and %LGE mass were separately included in the multivariable analysis.