Fig. 3 | Scientific Reports

Fig. 3

From: High Ano1 expression as key driver of resistance to radiation and cisplatin in HPV-negative head and neck squamous cell carcinoma

Fig. 3

Functional characterization of CCND1 and ANO1KD. (A)CCND1 and ANO1 KD significantly reduced the cell growth kinetic of FaDu compared to the control LeGo; (B) The plating efficiency is affected on ANO1 KD but not CCND1 KD, although the cell confluency is impaired for both KD (C, D); (E)CCND1 KD resulted in G0/G1 phase arrest and a simultaneous reduction of the S-phase fraction. Bars represent ± SEM from three independent experiments; (F) The knockdown of CCND1 and ANO1 significantly reduce the cell metabolic activity, measured by MTT assay.

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