Fig. 3 | Scientific Reports

Fig. 3

From: Regenerative effect of lyophilized dental follicle mesenchymal stem cells and platelet-rich fibrin in skin wounds in geriatric and young rats

Fig. 3

Histopathological evaluation of wounds at 15 days (x100 magnification). (a) Group 1, loss of tissue integrity, granulation tissue, inflammatory cells, loss of epithelium is observed, (b) Group 2, loss of tissue integrity, granulation tissue, inflammatory cells, the epithelial loss is observed, (c) Group 3, tissue integrity is partial, low epithelialization, (d) Group 4, and (e) Group 5, high rate of epithelialization, tissue integrity is largely maintained, mild granulation tissue, (f) Group 6, high level of epithelialization where tissue integrity is largely maintained, (g) Group 7, complete epithelialization, full tissue integrity, (h) Group 8, full tissue integrity, complete epithelialization was observed with hematoxylin-eosin staining microscope images. (i) Statistical analysis for inflammatory cells scoring. (j) Statistical analysis for epithelization scoring. (k) Statistical analysis for fibroblastic proliferation scoring. (l) Statistical analysis for scar-free healing. Arrows show fibroblastic proliferation, and stars show granulation tissue. In the bar chart red stars indicate the significance, triangles, squares or circles are distribution of individuals. The significance level of study groups is calculated based on SD.

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