Table 6 Comparison of the obesity group (n = 60) according to TLR2 (Arg753Gln) genotypes.

From: Serum levels of Wnt5a in Egyptian women with obesity and their association with toll like receptor 2 Arg753Gln gene polymorphism in a pilot case control study of obesity as a state of metaflammation

Obesity group (n = 60)

TLR2 (Arg753Gln) gene polymorphism

Mann-Whitney test

AA + GA

GG

Median

IQR

Median

IQR

Z

p-value

Age (years)

47.00

37.00–48.00

46.00

34.00–62.00

0.041

0.967

Weight (Kg)

84.00

75.00–90.00

90.00

84.75–103.00

1.898

0.058

Height (cm)

158.00

155.00–160.00

160.00

153.50–162.00

0.291

0.771

BMI (Kg/m2)

31.20

30.70–35.50

37.80

33.00–40.65

2.351

0.019*

Waist circumference (cm)

100.00

98.00–115.00

116.00

107.00–123.00

2.155

0.031*

Hip circumference (cm)

117.00

114.00–125.00

126.00

120.00–132.00

2.508

0.012*

WHR

0.90

0.84–0.90

0.90

0.84–0.92

0.104

0.917

FMI (Kg/m2)

15.00

13.00–16.00

17.40

14.75–19.45

1.927

0.054

FBS (mg/dL)

100.00

87.00–109.00

116.00

107.50–135.00

2.278

0.023*

ESR (mm/hr)

20.00

13.00–28.00

30.00

13.00–55.00

1.320

0.187

Cholesterol (mg/dL)

186.00

154.00–186.00

205.00

186.00–226.00

2.042

0.041*

Triglycerides (mg/dL)

145.00

145.00–145.00

155.00

145.00–178.00

1.574

0.116

HDL-C (mg/dL)

49.00

49.00–54.00

50.00

48.00–65.00

0.438

0.661

LDL-C (mg/dL)

147.00

147.00–165.00

181.00

147.00–190.00

2.026

0.043*

Leptin (ng/mL)

50.00

42.50–55.50

60.50

55.00–75.25

2.375

0.018*

TNF-α (pg/mL)

125.00

122.00–130.00

180.00

125.00–405.00

2.244

0.025*

Wnt5a (ng/mL)

3.50

3.10–3.70

5.50

4.70–7.00

4.484

< 0.001*

  1. BMI: Body mass index; ESR: Erythrocyte sedimentation rate; FMI: Fat mass index; HDL-C: High density lipoprotein cholesterol; LDL-C: Low density lipoprotein cholesterol; FBS: Fasting blood sugar; TNF-α: Tumor necrosis factor alpha; WHR: Waist-Hip ratio.
  2. *p-value < 0.05 indicates statistical significance.