Fig. 3

Risk model construction and survival analysis. (A) Univariate Cox regression analysis of the ten DEMRGs most closely related to OS. (B) The LASSO coefficient profiles of the eight MRGs used to construct the risk model. (C) Penalty plot for the LASSO regression model. (D,E) Heatmaps illustrate the expression patterns of the eight MRGs between low-risk and high-risk groups in the training (D) and testing (E) cohorts. (F,G) KM survival analysis for the OS (F) and DSS (G) between two risk groups in the training cohort. (H,I) KM survival analysis for the OS (H) and DSS (I) analysis between two risk groups in the testing cohort. (J,K) Time-dependent ROC analysis for predicting 1-year, 3-year, and 5-year OS (J) and DSS (K) in the training cohort. (L,M) Time-dependent ROC analysis for predicting 1-year, 3-year, and 5-year OS (L) and DSS (M) in the testing cohort.