Table 2 Comparison of the diagnostic efficiency of the various BI-RADS, SWE, and CEUS quantitative parameters in characterizing BLs.
Variable | Cut-off value | AUC (95% CI) | p-value | Sensitivity (95% CI) | Specificity (95% CI) | Positive predictive value (95% CI) | Negative predictive value (95% CI) |
|---|---|---|---|---|---|---|---|
BI-RADS | – | 0.729(0.638, 0.820) | < 0.001 | 0.514(0.349, 0.680) | 0.921(0.860, 0.982) | 0.793(0.790, 0.796) | 0.750(0.577, 0.923) |
SWE_Mean (kPa) | 41.750 | 0.737(0.629, 0.846) | < 0.001* | 0.600(0.438, 0.762) | 0.855(0.776, 0.934) | 0.775(0.772, 0.778) | 0.656(0.492, 0.821) |
SWE_Min (kPa) | 40.450 | 0.755(0.659, 0.852) | < 0.001* | 0.543(0.378, 0.708) | 0.895(0.826, 0.964) | 0.784(0.781, 0.787) | 0.704(0.531, 0.876) |
SWE_Max (kPa) | 46.800 | 0.757(0.648, 0.865) | < 0.001* | 0.686(0.532, 0.840) | 0.803(0.713, 0.892) | 0.766(0.763, 0.769) | 0.615(0.463, 0.768) |
EM ratio | 4.300 | 0.616(0.500, 0.733) | 0.975 | 0.514(0.349, 0.680) | 0.711(0.609, 0.812) | 0.649(0.645, 0.653) | 0.450(0.296, 0.604) |
AT | 0.205 | 0.473(0.362, 0.584) | 0.312 | 0.343(0.186, 0.500) | 0.724(0.623, 0.824) | 0.604(0.599, 0.608) | 0.364(0.200, 0.528) |
TTP | 15.065 | 0.557(0.442, 0.672) | 0.834 | 0.857(0.741, 0.973) | 0.316(0.211, 0.420) | 0.486(0.482, 0.491) | 0.366(0.262, 0.470) |
PI | 22.415 | 0.720(0.612, 0.827) | < 0.001* | 0.543(0.378, 0.708) | 0.855(0.776, 0.934) | 0.757(0.754, 0.760) | 0.633(0.461, 0.806) |
AS | 0.740 | 0.563(0.444, 0.681) | 0.856 | 0.429(0.265, 0.593) | 0.737(0.638, 0.836) | 0.640(0.636, 0.644) | 0.429(0.265, 0.593) |
AUC | 1750.045 | 0.717(0.609, 0.826) | < 0.001* | 0.600(0.438, 0.762) | 0.855(0.776, 0.934) | 0.775(0.772, 0.778) | 0.656(0.492, 0.821) |
BI | 15.060 | 0.474(0.360, 0.588) | 0.332 | 0.421(0.310, 0.532) | 0.629(0.468, 0.789) | 0.486(0.482, 0.491) | 0.711(0.579, 0.844) |
DT/2 | 90.405 | 0.516(0.395, 0.638) | 0.610 | 0.343(0.186, 0.500) | 0.789(0.698, 0.881) | 0.649(0.645, 0.653) | 0.429(0.245, 0.612) |
DS | 0.155 | 0.548(0.424, 0.673) | 0.795 | 0.486(0.320, 0.651) | 0.671(0.565, 0.777) | 0.613(0.608, 0.617) | 0.405(0.256, 0.553) |
