Table 4 Effect of motor and olfactory subtype interaction on estimated values: a GLM analysis adjusted for age, sex, disease duration, and LEDD.

From: The added value of anosmic subtype on motor subtype in Parkinson’s disease: a pilot study

 

PIGD NA as reference

TDPD TA as reference

TDPD NA as reference

B

95% CI

p value

B

95% CI

p value

B

95% CI

p value

Total

PIGD TA

2.504

− 6.15, 11.16

0.5680

7.459

− 1.31, 16.23

0.0950

15.528

5.62, 25.43

0.0024*

PIGD NA

1.000

4.955

− 4.64, 14.55

0.3088

13.024

2.65, 23.39

0.0143*

TDPD TA

− 4.955

− 14.55, 4.64

0.3088

1.000

8.069

− 2.15, 18.28

0.1205

TDPD NA

− 13.024

− 23.39, − 2.65

0.0143*

− 8.069

− 18.28, 2.15

0.1205

1.000

Part III

PIGD TA

2.073

− 3.70, 7.85

0.4790

− 0.517

− 6.37, 5.34

0.8615

5.660

− 0.95, 12.27

0.0926

PIGD NA

1.000

− 2.590

− 8.99, 3.81

0.4249

3.588

− 3.33, 10.51

0.3069

TDPD TA

2.590

− 3.81, 8.99

0.4249

1.000

6.178

− 0.64, 12.99

0.0753

TDPD NA

− 3.588

− 10.51, 3.33

0.3069

− 6.178

− 12.99, 0.64

0.0753

1.000

MoCA

PIGD TA

0.136

− 1.95, 2.22

0.8972

0.784

− 1.33, 2.90

0.4648

− 1.823

− 4.21, 0.57

0.1334

PIGD NA

1.000

0.647

− 1.68, 2.97

0.5827

− 1.959

− 4.47, 0.55

0.1253

TDPD TA

− 0.647

− 2.97, 1.68

0.5827

1.000

− 2.606

− 5.08, − 0.13

0.0392

TDPD NA

1.959

− 0.55, 4.47

0.1253

2.606

0.13, 5.08

0.0392

1.000

PDQ-39 SI

PIGD TA

3.685

− 3.20, 10.57

0.2918

8.787

1.80, 15.77

0.0141*

9.456

1.57, 17.34

0.0191

PIGD NA

1.000

5.102

− 2.57, 12.78

0.1907

5.770

− 2.52, 14.06

0.1710

TDPD TA

− 5.102

− 12.78, 2.57

0.1907

1.000

0.668

− 7.50, 8.84

0.8717

TDPD NA

− 5.770

− 14.06, 2.52

0.1710

− 0.668

− 8.84, 7.50

0.8717

1.000

  1. Table 4 presents clinical scores, including M-UPDRS total, M-UPDRS part III, MoCA, and PDQ-39 SI, adjusted for age, sex, disease duration, and LEDD using the general linear model (GLM).
  2. B, beta coefficient; CI, confidence interval; GLM, general linear model; LEDD, Levodopa equivalent daily dose; MoCA, Montreal Cognitive Assessment; M-UPDRS, Movement Disorder Society-Sponsored Revision of the Unified Parkinson’s Disease Rating Scale; NA, Non-anosmia; PDQ-39 SI, 39-item Parkinson’s Disease Questionnaire Summary index; PIGD, postural instability and gait disturbance; TA, total-anosmia; TDPD, Tremor-dominant Parkinson’s disease.
  3. * Two-tailed p < 0.0167, adjusted using the Bonferroni method.
  4. Two-tailed p < 0.0042, adjusted using the Bonferroni method to further account for comparisons across four clinical outcomes.