Fig. 6
From: 20-HETE mediates Ang II-induced cardiac hypertrophy via ROS and Ca2+ signaling in H9c2 cells
Inhibition of 20-HETE production or blockade of its action attenuates Ang II-induced phosphorylation of ERK1/2 and Akt in H9c2 cells. The total and phosphorylated levels of ERK1/2 and Akt proteins were detected and quantified. (A) Representative blots and quantification of p-ERK1/2 protein expression in the indicated groups. *P < 0.05 vs. Control group, #P < 0.05 vs. Ang II or 20-HETE group, n = 3. (B) Representative blots and quantification of p-Akt in the indicated groups. *P < 0.05 vs. Control group, #P < 0.05 vs. Ang II or 20-HETE group, n = 3.
