Fig. 2
From: B cells enhance IL-1 beta driven invasiveness in triple negative breast cancer
(a) Western blot analysis showing significantly increased phosphorylation of the p65 subunit of the NFκB complex in tumor cells 24 h after co-culture with EBV-B cells as compared to control cells. (b) Nuclear localization of P65 after co-culture with EBV-B cells can be blocked by addition of IKK inhibitor Bay 11-7085 in SUM159 (b) and MCF12A (c) cells. (d) Nuclear localization of P65 after co-culture with EBV-B cells can be blocked by addition of an IL-1 receptor antagonist (IL-1RA) in TNBC cells. Graphs show the mean of at least three independent experiments. Error bars represent standard deviations and significance is indicated by asterisk, *p < 0.05, **p < 0.01, ***p < 0.001.
