Fig. 3 | Scientific Reports

Fig. 3

From: Tofacitinib and budesonide treatment affect stemness and chemokine release in IBD patient-derived colonoids

Fig. 3

Donor-dependent effects of tofacitinib and budesonide treatment on colonoid size. The violin plots show individual sizes of 600–1200 colonoids in response to vehicle control (DMSO 0.033%), tofacitinib and budesonide treatment for N = 8 donors (5HC and 3UC) at (a) 2% and (b) 20% oxygen. Each dot represents one colonoid. Differences were evaluated using RM one-way ANOVA. *P < 0.05, *** P < 0.001, **** P < 0.0001.

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