Fig. 1

In vivo confocal microscopy image capture and CNN architecture. (A) InVivage confocal endomicroscope (Optiscan Imaging Ltd, Australia) with handheld probe (inset) (B) Captured image stacks in an en face orientation extended up to 400 μm depth into the oral epithelium, (C) Schematic of a captured of image stack along the z axis, (D) The modified Inception_v3 CNN architecture for the PMAC diagnostic models.