Table 4 Comparison of the sensitivity, specificity, positive predict value, negative predict value, and accuracy among four methods in patients with CM.

From: Comparison of mNGS with conventional methods for diagnosis of cryptococcal meningitis: a retrospective study

Method

Sensitivity (%)

Specificity (%)

Positive predict value (%)

Negative predict value (%)

Accuracy (%)

India ink

79.5 (35/44)

100 (20/20)

100 (35/35)

69.0 (20/29)

85.9 (55/64)

culture

63.4 (26/41)

100 (20/20)

100 (26/26)

57.1 (20/35)

75.4 (46/61)

CrAg

96.7 (29/30)

95.0 (19/20)

96.7 (29/30)

95.0 (19/20)

96.0 (48/50)

mNGS

92.0 (23/25)

100 (20/20)

100 (23/23)

90.9 (20/22)

95.6 (43/45)