Fig. 5
Top five up-regulated and down-regulated genes identified in L. catla ‘s brain and liver transcriptome on CYP exposure. The green and ash color indicates the top five upregulated genes in the brain and liver transcriptome, respectively and the red and orange color indicates the top five down-regulated genes in the brain and liver transcriptome, respectively. Abbreviations: proto-oncogene protein c-fos (fosab); growth arrest and DNA-damage-inducible protein (gadd45ba); metastasis-suppressor KiSS-1 (kiss1); protein BTG2 (btg2); nuclear receptor subfamily 4 (nr4a1); calcium homeostasis (calhm3); FMS-like tyrosine kinase 4 (flt4); deoxycytidylate deaminase (dctd); neuropeptide Y receptor type 1 (npy1r); methylenetetrahydrofolate reductase (NADPH) (mthfr); cytochrome P450 family 1 subfamily A (cyp1a); serine/threonine-protein kinase SIK1 (sik1); Delta14-sterol reductase (tm7sf2); diphosphomevalonate decarboxylase (mvda); isopentenyl-diphosphate (idi1); arginase (arg1); apolipoprotein A-I (apoa1a); cholesterol 7alpha-monooxygenase (cyp7a1); perilipin-2 (plin2); elongation of very long chain fatty acids protein 6 (elovl6).
